| CPU | Intel® Socket 2066 Core™ X-Series Processors |
| Chipset | Intel® X299 |
| Memory | 8 x DIMM, Max. 128GB, DDR4 4133(O.C.)/4000(O.C.)/3600(O.C.)/2666/2400/2133 MHz ECC, Non-ECC, Un-buffered Memory |
| 4 x DIMM, Max. 64GB, DDR4 4133(O.C.)/4000(O.C.)/3600(O.C.)/2666/2400/2133 MHz ECC, Non-ECC, Un-buffered Memory for Intel® Core™ X-series (4-core) | |
| Multi-GPU Support | NVIDIA® Quad-GPU SLI™, NVIDIA® 3-Way SLI™, NVIDIA® SLI™ 2-Way, AMD Quad-GPU CrossFireX™, AMD 3-Way CrossFireX™ |
| Expansion Slots | - 3 x PCIe 3.0/2.0 x16 (x16, x16/x16, x16/x16/x8) |
| - 1 x PCIe 3.0 x4 (max at x2 mode) *1 | |
| - 2 x PCIe 3.0/2.0 x1 | |
| Storage | - 1 x M.2 x4 Socket 3 (SATA & PCIE 3.0 x4) |
| - 1 x M.2 x4 Socket 3 (PCIE 3.0 x4) | |
| - 6 x SATA 6Gb/s | |
| LAN | Intel® I219V Gigabit LAN with Turbo LAN |
| Audio | Realtek® ALC S1220A 8-channel HD Audio CODEC |
| USB Ports | - ASMedia® USB 3.1: 2 x USB 3.1 Gen 2 (Type-A) |
| - Intel® X299 Chipset: 8 x USB 3.1 Gen 1, 6 x USB 2.0 | |
| Special Features | - ASUS Pro Clock Technology |
| - TUF Engine! Power Design |
